Study terminated after the first 40 patients due to high sedation failure rate. The mean onset in the midazolam group was 32 min and duration 40 min vs 30 and 50 min, respectively, in the chloral hydrate group. A year of the study period was excluded due to a change in the sedation policy. 1 had prolonged sedation of 2 h 10 min and 1 had a transient self-resolving drop in Sa O2 from 99% to 92%. 18% of the chloral hydrate group experienced anxiety vs 8% of the midazolam group (p=not significant).Behavioural disturbances and aggression in the emergency department is an increasing problem confronting emergency clinicians every day.The NICE guideline for sedation in children and young people advises that midazolam or chloral hydrate can be used to sedate for painless procedures.You wonder which of these drugs is the most effective and safe and which has the least side effects.The information from the scan is then used to help with diagnosis and plan their treatment.
A total of 151 abstracts were reviewed and seven relevant articles were found (table 1).A 2-year-old child is acutely admitted at night to a district general hospital following a prolonged focal seizure.A CT scan of the head without sedation fails as the child is too active and distressed, and as the on-call paediatric registrar, you are requested by the radiographer to prescribe a sedative.The therapies introduced in this brief article, acepromazine, gabapentin, trazadone, and melatonin, are meant to supplement low stress handling (e.g.bringing overly aggressive dogs directly into an exam room vs.